Dr. Adrian James Tett

Adrian Tett’s group develops and utilises computational approaches combined with metagenomics to understand the human microbiome in fine detail. Specifically, the group explores the hidden diversity in novel species and subspecies and its relationship to health or disease. Adrian’s group exploits the thousands of available metagenomes and uses large-scale metanalyses to identify and target potentially important microbiome members for further analysis and characterisation. For instance, the group was involved in revealing the gut bacterium Prevotella copri to be far more diverse than appreciated, which, with further ongoing characterisation, may explain the conflicting reports of P. copri in human health. Another focus is utilising ancient microbial fossils and pre-industrialised populations to determine how industrialisation has dramatically and rapidly changed the co-evolved human microbiome and the potential implications on human health.