Univ. Prof. Dr. Thomas Rattei

 

 

 

 

 

Head of the Division of Computational Systems Biology
Vice-head of the Department of Microbiology and Ecosystem Science

☎ +43 1 4277 91280

thomas.rattei@univie.ac.at 

Thomas Rattei’s work covers a wide spectrum of topics from bioinformatics, genome and metagenome analysis and systems biology. He has long-standing expertise in developing and applying computational methods for the interpretation of large-scale sequence information. The international reputation of his research group triggered their involvement in numerous international (meta-) genome sequencing and analysis consortia.

Thomas’ research activities not only cover individual, project-specific questions but also general problems in bioinformatics, computational infrastructure, and large-scale biological databases. Furthermore, his group develops novel, genome-based computational approaches for studying molecular inter-species interactions, such as between hosts and pathogens, between symbionts, or in microbial ecosystems.

Thomas and his team maintain and develop internationally relevant resources in computational biology, such as the web portals phendb.org, vogdb.org and effectivedb.org for microbial trait prediction, virus orthologous groups and protein families, and bacterial secreted proteins and secretion systems.

Links

Teaching

To explore Thomas' teaching activities at the University of Vienna, visit u:find.

Join the Team

If you are interested in joining the lab, explore open positions here or email Thomas directly.

Group Members

  • Michael Neumayer
  • Alexander Pfundner
  • Michael Predl
  • Roko Sango
  • Lovro Trgovec-Greif

 Publications

Huerta-Cepas J, Szklarczyk D, Heller D, Hernández-Plaza A, Forslund SK, Cook H et al. eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses. Nucleic Acids Research. 2019 Jan 8;47(D1):D309–D314. gky1085. Epub 2018 Nov 12. doi: 10.1093/nar/gky1085

Roux S, Adriaenssens EM, Dutilh BE, Koonin EV, Kropinski AM, Krupovic M et al. Minimum Information about an Uncultivated Virus Genome (MIUViG). Nature Biotechnology. 2019 Jan 1;37(1):29-37. Epub 2018 Dec 17. doi: 10.1038/nbt.4306

Hannemann L, Lucaciu CR, Sharma S, Rattei T, Mayer KFX, Gierl A et al. A promiscuous beta-glucosidase is involved in benzoxazinoid deglycosylation in Lamium galeobdolon. Phytochemistry. 2018 Dec;156:224-233. Epub 2018 Oct 15. doi: 10.1016/j.phytochem.2018.10.012

Liutkeviciute Z, Gil-Mansilla E, Eder T, Casillas-Perez B, Di Giglio MG, Muratspahic E et al. Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. The FASEB Journal. 2018 Dec;32(12):6808-6821. doi: 10.1096/fj.201800443

Springer K, Sänger PA, Moritz C, Felsl A, Rattei T, Fuchs TM. Insecticidal Toxicity of Yersinia frederiksenii Involves the Novel Enterotoxin YacT. Frontiers in Cellular and Infection Microbiology. 2018 Nov 14;8:392. doi: 10.3389/fcimb.2018.00392

Gerner SM, Rattei T, Graf AB. Assessment of urban microbiome assemblies with the help of targeted in silico gold standards. Biology direct. 2018 Oct 12;13(1):22. 22. doi: 10.1186/s13062-018-0225-6

Vázquez-Castellanos JF, Serrano-Villar S, Jiménez-Hernández N, Soto Del Rio MD, Gayo S, Rojo D et al. Interplay between gut microbiota metabolism and inflammation in HIV infection. The ISME Journal: multidisciplinary journal of microbial ecology. 2018 Aug;12(8):1964-1976. doi: 10.1038/s41396-018-0151-8

Maixner F, Turaev D, Cazenave-Gassiot A, Janko M, Krause-Kyora B, Hoopmann MR et al. The Iceman's Last Meal Consisted of Fat, Wild Meat, and Cereals. Current Biology. 2018 Jul 23;28(14):2348-2355.e9. doi: 10.1016/j.cub.2018.05.067

Genome Standards Consortium, Schirmi L, Banfield JF, Hugenholtz P, Woyke T. Corrigendum: Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea. Nature Biotechnology. 2018 Jul 6;36(7):660-660. 660. doi: 10.1038/nbt0718-660a

Hausmann B, Pelikan C, Herbold CW, Köstlbacher S, Albertsen M, Eichorst SA et al. Peatland Acidobacteria with a dissimilatory sulfur metabolism. The ISME Journal: multidisciplinary journal of microbial ecology. 2018 Jul;12(7):1729–1742. Epub 2018 Feb 23. doi: 10.1038/s41396-018-0077-1