Univ. Prof. Dr. Thomas Rattei

 

 

 

 

 

Head of the Division of Computational Systems Biology
Vice-head of the Department of Microbiology and Ecosystem Science

☎ +43 1 4277 91280

thomas.rattei@univie.ac.at 

Thomas Rattei’s work covers a wide spectrum of topics from bioinformatics, genome and metagenome analysis and systems biology. He has long-standing expertise in developing and applying computational methods for the interpretation of large-scale sequence information. The international reputation of his research group triggered their involvement in numerous international (meta-) genome sequencing and analysis consortia.

Thomas’ research activities not only cover individual, project-specific questions but also general problems in bioinformatics, computational infrastructure, and large-scale biological databases. Furthermore, his group develops novel, genome-based computational approaches for studying molecular inter-species interactions, such as between hosts and pathogens, between symbionts, or in microbial ecosystems.

Thomas and his team maintain and develop internationally relevant resources in computational biology, such as the web portals phendb.org, vogdb.org and effectivedb.org for microbial trait prediction, virus orthologous groups and protein families, and bacterial secreted proteins and secretion systems.

Links

Teaching

To explore Thomas' teaching activities at the University of Vienna, visit u:find.

Join the Team

If you are interested in joining the lab, explore open positions here or email Thomas directly.

Group Members

  • Michael Neumayer
  • Alexander Pfundner
  • Michael Predl
  • Roko Sango
  • Lovro Trgovec-Greif

 Publications

Spang A, Hatzenpichler R, Brochier-Armanet C, Rattei T, Tischler P, Spieck E et al. Distinct gene set in two different lineages of ammonia-oxidizing archaea supports the phylum Thaumarchaeota. Trends in Microbiology. 2010;18(8):331-340. doi: 10.1016/j.tim.2010.06.003

Kriehuber T, Rattei T, Weinmaier T, Bepperling A, Haslbeck M, Buchner J. Independent evolution of the core domain and its flanking sequences in small heat shock proteins. The FASEB Journal. 2010;24(10):3633-3642. doi: 10.1096/fj.10-156992

Lang S, Gruber K, Mihajlovic S, Arnold R, Gruber CJ, Steinlechner S et al. Molecular recognition determinants for type IV secretion of diverse families of conjugative relaxases. Molecular Microbiology. 2010;78(6):1539-1555. doi: 10.1111/j.1365-2958.2010.07423.x

Rattei T, Tischler P, Götz S, Jehl MA, Hoser J, Arnold R et al. SIMAP - a comprehensive database of pre-calculated protein sequence similarities, domains, annotations and clusters. Nucleic Acids Research. 2010;38(1):223-226. doi: 10.1093/nar/gkp949

Chapman J, Kirkness EF, Simakov O, Hampson SE, Mitros T, Weinmaier T et al. The dynamic genome of Hydra. Nature. 2010;464(7288):592-596. doi: 10.1038/nature08830