Univ. Prof. Dr. Thomas Rattei

 

 

 

 

 

Head of the Division of Computational Systems Biology
Vice-head of the Department of Microbiology and Ecosystem Science

☎ +43 1 4277 91280

thomas.rattei@univie.ac.at 

Thomas Rattei’s work covers a wide spectrum of topics from bioinformatics, genome and metagenome analysis and systems biology. He has long-standing expertise in developing and applying computational methods for the interpretation of large-scale sequence information. The international reputation of his research group triggered their involvement in numerous international (meta-) genome sequencing and analysis consortia.

Thomas’ research activities not only cover individual, project-specific questions but also general problems in bioinformatics, computational infrastructure, and large-scale biological databases. Furthermore, his group develops novel, genome-based computational approaches for studying molecular inter-species interactions, such as between hosts and pathogens, between symbionts, or in microbial ecosystems.

Thomas and his team maintain and develop internationally relevant resources in computational biology, such as the web portals phendb.org, vogdb.org and effectivedb.org for microbial trait prediction, virus orthologous groups and protein families, and bacterial secreted proteins and secretion systems.

Links

Teaching

To explore Thomas' teaching activities at the University of Vienna, visit u:find.

Join the Team

If you are interested in joining the lab, explore open positions here or email Thomas directly.

Group Members

  • Michael Neumayer
  • Alexander Pfundner
  • Michael Predl
  • Roko Sango
  • Lovro Trgovec-Greif

 Publications

Heinz E, Williams TA, Nakjang S, Noël CJ, Swan DC, Goldberg AV et al. The genome of the obligate intracellular parasite Trachipleistophora hominis: new insights into microsporidian genome dynamics and reductive evolution. PLoS Pathogens. 2012;8(10):e1002979. doi: 10.1371/journal.ppat.1002979

Horn A, Tischler P, Weinmaier T, Penz T, Heinz E, Brunham RC et al. Unity in Variety - The Pan-Genome of the Chlamydiae. Molecular Biology and Evolution. 2011 Dec;28(12):3253-3270. doi: 10.1093/molbev/msr161

Götz S, Arnold R, Sebastian-Leon P, Martin-Rodriguez S, Tischler P, Jehl MA et al. B2G-FAR, a species-centered GO annotation repository. Bioinformatics. 2011;27(7):919-924. doi: 10.1093/bioinformatics/btr059

Jehl MA, Arnold R, Rattei T. Effective-a database of predicted secreted bacterial proteins. Nucleic Acids Research. 2011;39(Suppl. 1):591-595. doi: 10.1093/nar/gkq1154

Nuk MR, Reisner A, Neuwirth M, Schilcher K, Arnold R, Jehl MA et al. Functional analysis of the finO distal region of plasmid R1. Plasmid. 2011;65(2):159-168. doi: 10.1016/j.plasmid.2010.12.002

Bergmann F, Selesi D, Weinmaier T, Tischler P, Rattei T, Meckenstock R. Genomic insights into the metabolic potential of the polycyclic aromatic hydrocarbon degrading sulfate-reducing Deltaproteobacterium N47. Environmental Microbiology. 2011;13(5):1125-1137. doi: 10.1111/j.1462-2920.2010.02391.x

Mewes HW, Ruepp A, Theis F, Rattei T, Rattei T, Walter M et al. MIPS: curated databases and comprehensive secondary data resources in 2010. Nucleic Acids Research. 2011;39(Supl. 1):220-224. doi: 10.1093/nar/gkq1157