Univ. Prof. Dr. Thomas Rattei

 

 

 

 

 

Head of the Division of Computational Systems Biology
Vice-head of the Department of Microbiology and Ecosystem Science

☎ +43 1 4277 91280

thomas.rattei@univie.ac.at 

Thomas Rattei’s work covers a wide spectrum of topics from bioinformatics, genome and metagenome analysis and systems biology. He has long-standing expertise in developing and applying computational methods for the interpretation of large-scale sequence information. The international reputation of his research group triggered their involvement in numerous international (meta-) genome sequencing and analysis consortia.

Thomas’ research activities not only cover individual, project-specific questions but also general problems in bioinformatics, computational infrastructure, and large-scale biological databases. Furthermore, his group develops novel, genome-based computational approaches for studying molecular inter-species interactions, such as between hosts and pathogens, between symbionts, or in microbial ecosystems.

Thomas and his team maintain and develop internationally relevant resources in computational biology, such as the web portals phendb.org, vogdb.org and effectivedb.org for microbial trait prediction, virus orthologous groups and protein families, and bacterial secreted proteins and secretion systems.

Links

Teaching

To explore Thomas' teaching activities at the University of Vienna, visit u:find.

Join the Team

If you are interested in joining the lab, explore open positions here or email Thomas directly.

Group Members

  • Michael Neumayer
  • Alexander Pfundner
  • Michael Predl
  • Roko Sango
  • Lovro Trgovec-Greif

 Publications

Weinmaier T, Platzer A, Frank J, Hellinger HJ, Tischler P, Rattei T. ConsPred - a rule-based (re-)annotation framework for prokaryotic genomes. Bioinformatics. 2016 Jul 4;32(21):3327-3329. doi: 10.1093/bioinformatics/btw393

Bulat T, Smidak R, Sialana FJ, Jung G, Rattei T, Bilban M et al. Transcriptomic and Proteomic Analysis of Arion vulgaris-Proteins for Probably Successful Survival Strategies? PLoS ONE. 2016 Mar;11(3):e0150614. doi: 10.1371/journal.pone.0150614

Maixner F, Krause-Kyora B, Turaev D, Herbig A, Hoopmann MR, Hallows JL et al. The 5300-year-old Helicobacter pylori genome of the Iceman. Science. 2016 Jan 8;351(6269):162-165. doi: 10.1126/science.aad2545

Eichinger V, Nussbaumer T, Platzer A, Jehl MA, Arnold R, Rattei T. EffectiveDB-updates and novel features for a better annotation of bacterial secreted proteins and Type III, IV, VI secretion systems. Nucleic Acids Research. 2016 Jan 4;44(D1):D669–D674. doi: 10.1093/nar/gkv1269

Huerta-Cepas J, Szklarczyk D, Forslund K, Cook H, Heller D, Walter MC et al. eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences. Nucleic Acids Research. 2016 Jan 4;44(D1):D286–D293. doi: 10.1093/nar/gkv1248

Capel E, Zomer AL, Nussbaumer T, Bole C, Izac B, Frapy E et al. Comprehensive Identification of Meningococcal Genes and Small Noncoding RNAs Required for Host Cell Colonization. mBio. 2016;7(4):e01173-16. doi: 10.1128/mBio.01173-16

Laffy PW, Wood-Charlson EM, Turaev D, Weynberg KD, Botté ES, van Oppen MJH et al. HoloVir: A Workflow for Investigating the Diversity and Function of Viruses in Invertebrate Holobionts. Frontiers in Microbiology. 2016;7:822. doi: 10.3389/fmicb.2016.00822