Univ. Prof. Dr. Thomas Rattei

 

 

 

 

 

Head of the Division of Computational Systems Biology
Vice-head of the Department of Microbiology and Ecosystem Science

☎ +43 1 4277 91280

thomas.rattei@univie.ac.at 

Thomas Rattei’s work covers a wide spectrum of topics from bioinformatics, genome and metagenome analysis and systems biology. He has long-standing expertise in developing and applying computational methods for the interpretation of large-scale sequence information. The international reputation of his research group triggered their involvement in numerous international (meta-) genome sequencing and analysis consortia.

Thomas’ research activities not only cover individual, project-specific questions but also general problems in bioinformatics, computational infrastructure, and large-scale biological databases. Furthermore, his group develops novel, genome-based computational approaches for studying molecular inter-species interactions, such as between hosts and pathogens, between symbionts, or in microbial ecosystems.

Thomas and his team maintain and develop internationally relevant resources in computational biology, such as the web portals phendb.org, vogdb.org and effectivedb.org for microbial trait prediction, virus orthologous groups and protein families, and bacterial secreted proteins and secretion systems.

Links

Teaching

To explore Thomas' teaching activities at the University of Vienna, visit u:find.

Join the Team

If you are interested in joining the lab, explore open positions here or email Thomas directly.

Group Members

  • Michael Neumayer
  • Alexander Pfundner
  • Michael Predl
  • Roko Sango
  • Lovro Trgovec-Greif

 Publications

Marz M, Beerenwinkel N, Drosten C, Fricke M, Frishman D, Hofacker IL et al. Challenges in RNA virus bioinformatics. Bioinformatics. 2014 Jul 1;30(13):1793-1799. doi: 10.1093/bioinformatics/btu105

Walker A, Pfitzner B, Neschen S, Kahle M, Harir M, Lucio M et al. Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet. The ISME Journal: multidisciplinary journal of microbial ecology. 2014 Jun 6;8(12):2380–2396. doi: 10.1038/ismej.2014.79

Behrens S, Widder S, Mannala GK, Qing X, Madhugiri R, Kefer N et al. Ultra deep sequencing of Listeria monocytogenes sRNA transcriptome revealed new antisense RNAs. PLoS ONE. 2014 Feb 3;9(2):e83979. e83979. doi: 10.1371/journal.pone.0083979

Powell S, Forslund K, Szklarczyk D, Trachana K, Roth A, Huerta-Cepas J et al. eggNOG v4.0: nested orthology inference across 3686 organisms. Nucleic Acids Research. 2014 Jan;42(D1):D231-D239. doi: 10.1093/nar/gkt1253

Lagkouvardos I, Jehl MA, Rattei T, Horn M. Signature protein of the PVC superphylum. Applied and Environmental Microbiology. 2014 Jan;80(2):440-445. doi: 10.1128/AEM.02655-13

Probst AJ, Weinmaier T, Raymann K, Perras A, Emerson JB, Rattei T et al. Biology of a widespread uncultivated archaeon that contributes to carbon fixation in the subsurface. Nature Communications. 2014;5:5497. doi: 10.1038/ncomms6497

Tasara T, Weinmaier T, Klumpp J, Rattei T, Stephan R. Complete Genome Sequence of Listeria monocytogenes Lm60, a Strain with an Enhanced Cold Adaptation Capacity. Genome Announcements. 2014;2(6):e01248-14. doi: 10.1128/genomeA.01248-14

Hanak AM, Nagler M, Weinmaier T, Sun X, Fragner L, Schwab C et al. Draft Genome Sequence of the Growth-Promoting Endophyte Paenibacillus sp. P22, Isolated from Populus. Genome Announcements. 2014;2(2):e00276-14. e00276-14. Epub 2014 Apr 10. doi: 10.1128/genomeA.00276-14