Univ. Prof. Dr. Thomas Rattei

 

 

 

 

 

Head of the Division of Computational Systems Biology
Vice-head of the Department of Microbiology and Ecosystem Science

☎ +43 1 4277 91280

thomas.rattei@univie.ac.at 

Thomas Rattei’s work covers a wide spectrum of topics from bioinformatics, genome and metagenome analysis and systems biology. He has long-standing expertise in developing and applying computational methods for the interpretation of large-scale sequence information. The international reputation of his research group triggered their involvement in numerous international (meta-) genome sequencing and analysis consortia.

Thomas’ research activities not only cover individual, project-specific questions but also general problems in bioinformatics, computational infrastructure, and large-scale biological databases. Furthermore, his group develops novel, genome-based computational approaches for studying molecular inter-species interactions, such as between hosts and pathogens, between symbionts, or in microbial ecosystems.

Thomas and his team maintain and develop internationally relevant resources in computational biology, such as the web portals phendb.org, vogdb.org and effectivedb.org for microbial trait prediction, virus orthologous groups and protein families, and bacterial secreted proteins and secretion systems.

Links

Teaching

To explore Thomas' teaching activities at the University of Vienna, visit u:find.

Join the Team

If you are interested in joining the lab, explore open positions here or email Thomas directly.

Group Members

  • Michael Neumayer
  • Alexander Pfundner
  • Michael Predl
  • Roko Sango
  • Lovro Trgovec-Greif

 Publications

Bowers RM, Kyrpides NC, Stepanauskas R, Harmon-Smith M, Doud D, Reddy TBK et al. Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea. Nature Biotechnology. 2017 Aug 8;35(8):725-731. doi: 10.1038/nbt.3893

Thannesberger J, Hellinger HJ, Klymiuk I, Kastner MT, Rieder FJJ, Schneider M et al. Viruses comprise an extensive pool of mobile genetic elements in eukaryote cell cultures and human clinical samples. The FASEB Journal. 2017 May 1;31(5):1987-2000. Epub 2017 Feb 8. doi: 10.1096/fj.201601168R

Zojer M, Schuster LN, Schulz F, Pfundner A, Horn M, Rattei T. Variant profiling of evolving prokaryotic populations. PeerJ. 2017 Feb 16;5:e2997. doi: 10.7717/peerj.2997

Loy A, Pfann C, Steinberger M, Hanson B, Herp S, Brugiroux S et al. Lifestyle and Horizontal Gene Transfer-Mediated Evolution of Mucispirillum schaedleri, a Core Member of the Murine Gut Microbiota. mSystems. 2017 Feb 9;2(1):00171-16. doi: 10.1128/mSystems.00171-16

Di Giglio MG, Muttenthaler M, Harpsøe K, Liutkeviciute Z, Keov P, Eder T et al. Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. Scientific Reports. 2017 Feb 1;7:41002. doi: 10.1038/srep41002

Sato Y, Ling EYS, Turaev D, Laffy P, Weynberg KD, Rattei T et al. Unraveling the microbial processes of black band disease in corals through integrated genomics. Scientific Reports. 2017 Jan 17;7:40455. doi: 10.1038/srep40455

Weynberg KD, Laffy PW, Wood-Charlson EM, Turaev D, Rattei T, Webster NS et al. Coral-associated viral communities show high levels of diversity and host auxiliary functions. PeerJ. 2017;5:e4054. doi: 10.7717/peerj.4054

Capel E, Barnier JP, Zomer AL, Bole-Feysot C, Nussbaumer T, Jamet A et al. Peripheral blood vessels are a niche for blood-borne meningococci. Virulence. 2017;8(8):1808–1819. Epub 2017 Nov 27. doi: 10.1080/21505594.2017.1391446

Diesner SC, Bergmayr C, Pfitzner B, Assmann V, Krishnamurthy D, Starkl P et al. A distinct microbiota composition is associated with protection from food allergy in an oral mouse immunization model. Clinical Immunology. 2016 Dec;173:10–18. doi: 10.1016/j.clim.2016.10.009

Eder T, Grebien F, Rattei T. NVT: a fast and simple tool for the assessment of RNA-Seq normalization strategies. Bioinformatics. 2016 Aug 11;32(23):3682-3684. doi: 10.1093/bioinformatics/btw521