Univ. Prof. Dr. Thomas Rattei

 

 

 

 

 

Head of the Division of Computational Systems Biology
Vice-head of the Department of Microbiology and Ecosystem Science

☎ +43 1 4277 91280

thomas.rattei@univie.ac.at 

Thomas Rattei’s work covers a wide spectrum of topics from bioinformatics, genome and metagenome analysis and systems biology. He has long-standing expertise in developing and applying computational methods for the interpretation of large-scale sequence information. The international reputation of his research group triggered their involvement in numerous international (meta-) genome sequencing and analysis consortia.

Thomas’ research activities not only cover individual, project-specific questions but also general problems in bioinformatics, computational infrastructure, and large-scale biological databases. Furthermore, his group develops novel, genome-based computational approaches for studying molecular inter-species interactions, such as between hosts and pathogens, between symbionts, or in microbial ecosystems.

Thomas and his team maintain and develop internationally relevant resources in computational biology, such as the web portals phendb.org, vogdb.org and effectivedb.org for microbial trait prediction, virus orthologous groups and protein families, and bacterial secreted proteins and secretion systems.

Links

Teaching

To explore Thomas' teaching activities at the University of Vienna, visit u:find.

Join the Team

If you are interested in joining the lab, explore open positions here or email Thomas directly.

Group Members

  • Michael Neumayer
  • Alexander Pfundner
  • Michael Predl
  • Roko Sango
  • Lovro Trgovec-Greif

 Publications

Haselmair-Gosch C, Miosic S, Nitarska D, Roth BL, Walliser B, Paltram R et al. Great Cause-Small Effect: Undeclared Genetically Engineered Orange Petunias Harbor an Inefficient Dihydroflavonol 4-Reductase. Frontiers in Plant Science. 2018 Feb 28;9:149. doi: 10.3389/fpls.2018.00149

Felkel S, Vogl C, Rigler D, Jagannathan V, Leeb T, Fries R et al. Asian horses deepen the MSY phylogeny. Animal genetics. 2018 Feb;49(1):90-93. doi: 10.1111/age.12635

Shima K, Wanker M, Skilton RJ, Cutcliffe LT, Schnee C, Kohl TA et al. The Genetic Transformation of Chlamydia pneumoniae. mSphere. 2018;3(5):e00412-18. doi: 10.1128/mSphere.00412-18

Käding N, Kaufhold I, Müller C, Szaszák M, Shima K, Weinmaier T et al. Growth of Chlamydia pneumoniae Is Enhanced in Cell swith Impaired Mitochondrial Function. Frontiers in Cellular and Infection Microbiology. 2017 Dec 5;7:499. doi: 10.3389/fcimb.2017.00499

Eder T, Kobus S, Stallmann S, Stepanow S, Köhrer K, Hegemann JH et al. Genome sequencing of Chlamydia trachomatis serovars E and F reveals substantial genetic variation. Pathogens and Disease. 2017 Dec;75(9):ftx120. Epub 2017 Nov 24. doi: 10.1093/femspd/ftx120

Sczyrba A, Hofmann P, Belmann P, Koslicki D, Janssen S, Dröge J et al. Critical Assessment of Metagenome Interpretation-a benchmark of metagenomics software. Nature Methods. 2017 Oct 2;14(11):1063-1071. Epub 2017. doi: 10.1038/nmeth.4458

Walker A, Pfitzner B, Harir M, Schaubeck M, Calasan J, Heinzmann SS et al. Sulfonolipids as novel metabolite markers of Alistipes and Odoribacter affected by high-fat diets. Scientific Reports. 2017 Sep 8;7:11047. doi: 10.1038/s41598-017-10369-z

Bowers RM, Kyrpides NC, Stepanauskas R, Harmon-Smith M, Doud D, Reddy TBK et al. Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea. Nature Biotechnology. 2017 Aug 8;35(8):725-731. doi: 10.1038/nbt.3893

Thannesberger J, Hellinger H-J, Klymiuk I, Kastner M-T, Rieder FJJ, Schneider M et al. Viruses comprise an extensive pool of mobile genetic elements in eukaryote cell cultures and human clinical samples. The FASEB Journal. 2017 May 1;31(5):1987-2000. Epub 2017 Feb 8. doi: 10.1096/fj.201601168R

Zojer M, Schuster LN, Schulz F, Pfundner A, Horn M, Rattei T. Variant profiling of evolving prokaryotic populations. PeerJ. 2017 Feb 16;5:e2997. doi: 10.7717/peerj.2997