In metagenome analysis, computational methods for assembly, taxonomic profiling and binning are key components facilitating downstream biological data interpretation. However, a lack of consensus about benchmarking datasets and evaluation metrics complicates proper performance assessment. The Critical Assessment of Metagenome Interpretation ...
The Federal Ministry of Science, Research and Economics has granted a federal project to establish software and database infrastructure for life science. CUBE will coordinate this project, which has a total volume of 660k EUR from 2017 to 2020. The main ...
Orthologous groups are a central resource for comparative (meta-)genomics. At CUBE we have established a novel resource of Virus Orthologous Groups (VOGs), which is based all current RefSeq genomes. It therefore represents all viral lineages of which complete genomes are available. ...
Measuring differential gene expression is a common task in the analysis of RNA-Seq data. To identify differentially expressed genes between two samples, it is crucial to normalize the data sets. While multiple normalization methods are available, all of them are ...
HoloVir is a robust and flexible data analysis pipeline that provides an optimized and validated workflow for taxonomic and functional characterization of viral metagenomes derived from invertebrate holobionts. It has been ...
CONSPRED is a prokaryotic genome annotation framework that performs various intrinsic gene predictions, homology searches, predictions of non-coding genes, and complex features and integrates all evidence into a consensus annotation.
CONSPRED 1.28 has now been publicly released along with an applications ...
Raheleh has successfully defended her PhD thesis "ECF sigma factors: how endophytes sense the plants" this morning. The thesis was reviewed by Prof. Eva Stukenbrock, Kiel, and by Dr. Stefanie Wienkoop, University of Vienna. Congratulations, Raheleh!
During the afternoon of May 9th the planet mercury has (slightly) obstructed the sun. Mercury became visible in front of the sun at 13:12 and did not leave the sun until sunset. CUBE has observed the cosmic spectacle on the ...
