Dr. Harald Marx

University of Vienna
Althanstrasse 14
A-1090 Vienna
Phone: +43 1 4277
Phone Extension: 76687
Austria

THE PEPTIDOME: A TREASURE TROVE OF NOVEL PEPTIDE DRUGS

Bioactive peptides are pervasive across the tree of life, playing key roles in the gastrointestinal, cardiovascular, endocrine, nervous, and immune system. Antimicrobial peptides, natural occurring antibiotics, are of special interest in the race to fight multi-drug resistant pathogens. To study bioactive peptides, peptidomics is an emerging field in mass spectrometry (MS)-based proteomics. That said, proteomics experimental protocols and computational tools are mainly conceived to explore proteomes, but not the inherent peptidome. The overarching objective of my lab will be to devise computational tools and experimental protocols to facilitate peptidomic research.

PROJECTS

Master

Proteogenomic search space construction to explore microbial peptidomes

A community driven database to annotate and curate the peptidome

A classifier to assess spectrum quality in mass spectrometry-based proteomics

PhD

Coming soon.

LINKS

Google Scholar

LAB MEMBERS

Coming soon.